The PTGDS Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to L-PGDS, LPGDS, PGD2 synthase, and PTGDS. This antibody recognizes Human antigen. The PTGDS Antibody has been validated for the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep